This happens when there is problem with the working of the liver, or there is blood disease. This test is most often done when other blood tests suggest a condition called megaloblastic anemia. It aids the nerve cells, the RBCs and is even used to produce DNA in the cells. For the study, Ohio State University Comprehensive Cancer Center researchers examined 77,000 patients between the ages of 50 and 76 over a 10-year period. High Serum B12 Can Be Caused By A Functional B12 Deficiency. Hi, Question regarding my 2.5 year old son. There is a low-cost blood test available that can detect this genetic defect. A lack of vitamin B12 in the body can lead to vitamin deficiency anemia 1 2 4. If after the test, the doctor would identify that you have a little amount of the vitamin in your body, you may be advised to take in supplements to produce the balance. After a week, the haptocorrin-bound B12 is imported by the liver and recycled via the bile to the gut. High folate levels can also mean a vitamin B12 deficiency. Having too much folic acid in the blood is not a dangerous condition and does not cause other health issues. The relationship among vitamin B-12, folate and iron is a good example of the complex way in which some essential nutrients help keep your body healthy. Body cells need vitamin B12 to use folate. Low values No research has yet found any side effects from taking too much vitamin B-12. Vitamin B12 Overdose: the Vitamin B Complex. High levels of Vitamin B12 may be too much of a good thing. Pernicious anemia is a form of megaloblastic anemia caused by poor vitamin B12 absorption. Elevated blood levels of vitamin B12 are generally associated with increased amounts of proteins that carry vitamin B12 in the bloodstream or release of stored vitamin B12. If a significant amount of the vitamin B12 in your blood is inactive, a blood test may show that you have normal B12 levels, even though your body cannot use much of it. The serum vitamin B12 blood test isn’t reliable. “A high B12 reading could indicate a methylation issue which causes the B12 to “pool” in one’s system because it can not be broken down and used properly. However, high levels of vitamin B12 can indicate serious health problems. Ignore the blood test. My blood test cam back with a Folate Level of 28.1 ng/mL on a range of 3.1-17.5 and my B12 was 1,408.0 pg/mL on a range of 193.0-986.0. Dr said everything looked normal, but when he showed me the results the vit B12 was flagged as "high" at around 1400. Vitamin B12 is a very important vitamin for the body. This means that there is enough B12 in the body, but the cells are not able to use it, so they export it back to the blood, and it builds up there, bound to haptocorrin. But if you take supplements, you might ingest more than your body needs. If a ferritin test reveals that your blood ferritin level is lower than normal, it indicates your body's iron stores are low and you have iron deficiency. Both of these levels appear to be well above the ranges. Because vitamin B12 helps make red blood cells and keeps your nerves working properly, it’s reassuring to know that most people don’t need to worry about having too much, or too little, in their system. This can occur when the stomach makes less of the substance the body needs to properly absorb vitamin B12. Increased vitamin B12 levels are uncommon, because excess vitamin B12 is usually eliminated with urine. Vitamin B-12 (cobalamin) is a water-soluble vitamin that plays essential roles in red blood cell formation, cell metabolism, nerve function and the production of DNA. Consuming large amounts of the vitamin won’t make you sick. Pee may be bright yellow because it’s a water-soluble vitamin. Food sources of vitamin B-12 include poultry, meat, fish and dairy products. Vitamin B12 levels are measured through a vitamin B12 level blood test, also referred to as a cobalamin test, according to MedlinePlus. It helps form red blood cells. The risk comes from having high levels when you are NOT taking supplements. Vitamin B12 is a water-soluble vitamin, which means that when we ingest too much of it, the excess amounts are flushed out of the body through urine. Vitamin B12 is one of the 8 types of vitamins belonging to the B complex. Symptoms of too much vitamin B12 Dr Thornber said one of the signs of too much vitamin B12 is urine discolouration. Vitamin B12 test measures how much of the vitamin is in your blood. But a folate test is not a reliable way to test for a vitamin B12 deficiency. It is a vitamin that dissolves in water (water-soluble). So if vitamin B12 levels are very low, folate can't be used by the cells, and high levels of it may build up in the blood. 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